Fresh from inexplicably saving the galaxy, the Deadpool Corps is offered a mission by the Omega Confederation to squash a rebellion by the Krook people that is derailing the company's mining operation. Naturally, the Confederation is a little miffed upon learning the Corps has changed sides!
On a distant planet, a simple native population revolts against the mighty Omega Confederation. Since the Omega Confederation is paying a lot of money to the galaxy's top mercenaries - Hello, Deadpool Corps! - to put down this rebellion, it's no wonder they're a little miffed when Wade Wilson and company appear to have changed sides.